At present, he is mainly engaged in the neurobiology of mental illness, focusing on drug addiction and anxiety disorders. The main research interests are as follows: 1. starting from "reward and emotional memory", using neural loop research methods (such as photogenetics, chemical genetics, in vivo electrophysiological recording and optical fiber recording, etc.) and molecular biology, to study the neural loop and molecular mechanism of drug addiction and anxiety. 2. Systematic preclinical evaluation of new drugs for drug addiction and anxiety disorders by means of behavioral pharmacology.